Clinical Trial

Oral Cryotherapy Plus Acupressure and Acupuncture Versus Oral Cryotherapy for Decreasing Chemotherapy-Induced Peripheral Neuropathy From Oxaliplatin-Based Chemotherapy in Patients With Gastrointestinal Cancer

Investigator

Stacey A. Cohen, MD

Complete title:

Pilot Study of Oral Cryotherapy vs. Oral Cryotherapy Plus Acupuncture and Acupressure to Decrease Chemotherapy-Induced Peripheral Neuropathy from Oxaliplatin-Based Chemotherapy for GI cancers

Trial phase:

Phase II

Study ID:

NCT04505553

Local study ID:

RG1121095

Summary:

This phase II trial investigates how well oral cryotherapy plus acupressure and acupuncture compared with oral cryotherapy alone work in decreasing chemotherapy-induced peripheral neuropathy in patients with gastrointestinal cancer who are receiving oxaliplatin-based chemotherapy. Acupressure is the application of pressure or localized massage to specific sites on the body to control symptoms such as pain or nausea. Acupuncture is the technique of inserting thin needles through the skin at specific points on the body to control pain and other symptoms. Cryotherapy uses cold temperature such as oral ice chips to prevent abnormally increased pain sensation. Giving oral cryotherapy with acupressure and acupuncture may work better in decreasing chemotherapy-induced peripheral neuropathy from oxaliplatin-based chemotherapy in patients with gastrointestinal cancer compared to oral cryotherapy alone.

Trial keywords:

Anal Cancer, Colon Cancer, Esophageal Cancer, Gastric Cancer, Liver Cancer, Pancreatic Cancer, Rectal Cancer, Neuroendocrine Tumor, Digestive System Neoplasms, Intestinal Neoplasms

View Trial at NIH

Enrollment status:

Recruiting

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