Clinical Trial

A Study of CART-PSMA-TGFßRDN in Patients With Metastatic Castration Resistant Prostate Cancer

Investigator
Complete title:
CART-PSMA-TGFßRDN-02 A Phase 1 Open-Label, Multi-Center Study of PSMA Targeted Genetically Modified Chimeric Antigen Receptor T Cells in Patients with Metastatic Castration Resistant Prostate Cancer
Trial phase:
Phase I
Study ID:
NCT04227275
Local study ID:
10299
Summary:
Multi-center, open-label, Phase 1 study of the safety, tolerability and feasibility of dosing patients harboring metastatic castration resistant prostate cancer (mCRPC) with genetically modified autologous T cells (CART-PSMA-TGFßRDN cells) engineered to express a chimeric antigen receptor (CAR) capable of recognizing the tumor antigen prostate-specific membrane antigen (PSMA) and activating the T cell.
Trial keywords:
Prostate Cancer, Castration-resistant (CRPC)
Enrollment status:
Recruiting
Trial eligibility
** For Eligibility information, please click on the "Look up trial at NIH" link above **
Other eligibility criteria may apply.
Trial exclusions
Other exclusion criteria may apply.
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