Sarah S. Lee, MD

Fred Hutch
Assistant Professor, Division of Medical Oncology
University of Washington School of Medicine
Assistant Member, Clinical Research Division
Fred Hutch
Medical Oncology
“I’m grateful for the long-term relationships I develop with patients and families; together we work toward common goals, navigate unforeseen setbacks and celebrate milestones.”
— Dr. Lee
Why do you focus on treating patients with multiple myeloma and similar disorders?

Before going to medical school, I got a job in the clinical research department of a cancer center. I worked with an investigator who was testing new drug therapies for multiple myeloma, a type of cancer that affects cells in the immune system. It was the first time I had conducted research in a clinical setting, where I got to interact with patients and witness up close how scientific advances can directly impact people. The experience lit a fire that inspired me to continue working with this population of patients and to keep looking for opportunities to improve treatment options. It’s really exciting to see how quickly this area of medicine continues to evolve and to see patients with multiple myeloma and similar disorders living longer and enjoying a better quality of life.

What’s it like to work with you?

By the time some patients with plasma cell disorders see me, they have been feeling ill for a long period of time without understanding why or receiving a diagnosis, which can be a frustrating experience. From the moment we first meet, I focus on laying the groundwork for a trusting, positive relationship where you feel comfortable asking questions and talking openly about your concerns. I’m interested in learning about what your medical journey has been like so far and what’s important to you as an individual. I’m grateful for the long-term relationships I develop with patients and families; together we work toward common goals, manage unforeseen setbacks and celebrate milestones.

Provider background

Specialty: Medical Oncology

Area of clinical practice

Hematologic malignancies

Multiple myeloma, other plasma cell disorders

I am a hematologist-oncologist who specializes in the care of patients with plasma cell disorders. Plasma cells are a type of white blood cell that live in the bone marrow and help the body fight infection. Sometimes these cells don’t work as they should, developing into cancers such as multiple myeloma.

Before joining Fred Hutch, I completed a fellowship in hematology-oncology at the Cleveland Clinic. My background also includes experience in researching novel therapies for multiple myeloma, amyloidosis and other plasma cell disorders. What drew me to Fred Hutch was the opportunity to participate in clinical research  and to embrace a collaborative approach to medicine. It’s not any single physician taking care of you; there’s a whole team of experts working together to help you navigate the ups and downs of your diagnosis. 

Bone marrow The soft, spongy material in the center of your bones that produces all your blood cells, such as white blood cells, red blood cells and platelets. Hematologist A physician who specializes in diseases of the blood and blood-forming tissues. White blood cell A type of blood cell that is made in the bone marrow and found in the blood and lymph tissue. White blood cells are part of the body’s immune system and help the body fight infection and other diseases. A type of blood cell that is made in the bone marrow and found in the blood and lymph tissue. White blood cells are part of the body’s immune system. They help the body fight infection and other diseases. Types of white blood cells include granulocytes (neutrophils, eosinophils and basophils), monocytes and lymphocytes (T cells and B cells). Checking the number of white blood cells in the blood is usually part of a complete blood cell (CBC) test. It may be used to look for conditions such as infection, inflammation, allergies and leukemia. Also called leukocyte and WBC.

Diseases treated

Education, experience and certifications
Undergraduate Degree
University of California, Berkeley
Medical Degree
St. George's University School of Medicine
Rutgers New Jersey Medical School, Internal Medicine
Cleveland Clinic, Hematology-Oncology
Board Certification
Medical Oncology, 2017, American Board of Internal Medicine


Clinical trials

We make promising new treatments available to you through studies called clinical trials led by Fred Hutch doctors. Many of these trials at Fred Hutch have led to FDA-approved treatments and have improved standards of care globally. Together, you and your doctor can decide if a study is right for you.

Study ID:
A Study Comparing Talquetamab in Combination With Daratumumab or in Combination With Daratumumab and Pomalidomide Versus Daratumumab in Combination With Pomalidomide and Dexamethasone in Participants With Relapsed or Refractory Multiple Myeloma (MonumenTAL-3)
Complete title
A Phase 3 Randomized Study Comparing Talquetamab SC in Combination With Daratumumab SC and Pomalidomide (Tal-DP) or Talquetamab SC in Combination With Daratumumab SC (Tal-D) Versus Daratumumab SC, Pomalidomide and Dexamethasone (DPd), in Participants With Relapsed or Refractory Multiple Myeloma who Have Received at Least 1 Prior Line of Therapy
Study ID:
A Study to Evaluate the Efficacy and Safety of Birtamimab in Mayo Stage IV Patients With AL Amyloidosis (AFFIRM-AL)
Complete title
A Phase 3, Randomized, Multicenter, Double-Blind, Placebo-Controlled, Efficacy and Safety Study of Birtamimab Plus Standard of Care vs. Placebo Plus Standard of Care in Mayo Stage IV Subjects with Light Chain (AL) Amyloidosis


Many of our Fred Hutch doctors conduct ongoing research to improve standards of patient care. Their work is evaluated by other doctors and selected for publication to the United States National Library of Medicine, the largest medical library in the world. See scientific papers this Fred Hutch provider has written.


Our providers are often asked to give their medical expertise for press and news publications. Read articles by or about this Fred Hutch provider.

Your care team

At Fred Hutch, you receive care from a team of providers with extensive experience in your disease. Your team includes doctors, a patient care coordinator, a registered nurse, an advanced practice provider and others, based on your needs. You also have access to experts like nutritionists, social workers, acupuncturists, psychiatrists and more who specialize in supporting people with cancer or blood disorders.
Registered nurse (RN)
Registered nurse (RN)
Your nurse manages your care alongside your doctor and assists with care procedures and treatments.
Patient care coordinator
Patient care coordinator
Your patient care coordinator works closely with you and your doctor and serves as your scheduler.


Fred Hutch accepts most national private health insurance plans as well as Medicare. We also accept Medicaid for people from Washington, Alaska, Montana and Idaho. We are working to ensure that everyone, no matter what their financial situation, has access to the care they need.