Paul C. Hendrie, MD, PhD

Fred Hutch
Associate Professor, Hematology and Medicine
University of Washington School of Medicine
Medical Oncology, Hematology
“People often arrive at my office with symptoms but no diagnosis, feeling anxious, frustrated or frightened. It’s my job, when possible, to alleviate these feelings.”
— Dr. Hendrie
Why did you become a hematology specialist?

My interest in hematology began with my graduate research studying white blood cell development. During my time in the lab, I knew I wanted to pursue a career that combined research on blood diseases with caring for patients who have these diseases. As a physician, I get to be both a scientific expert and an advocate for patients like you.

White blood cell A type of blood cell that is made in the bone marrow and found in the blood and lymph tissue. White blood cells are part of the body’s immune system and help the body fight infection and other diseases. A type of blood cell that is made in the bone marrow and found in the blood and lymph tissue. White blood cells are part of the body’s immune system. They help the body fight infection and other diseases. Types of white blood cells include granulocytes (neutrophils, eosinophils and basophils), monocytes and lymphocytes (T cells and B cells). Checking the number of white blood cells in the blood is usually part of a complete blood cell (CBC) test. It may be used to look for conditions such as infection, inflammation, allergies and leukemia. Also called leukocyte and WBC.
What’s a consultation with you like?

Hematology consultations can be a lot like detective work. I search for the cause and identity of the problems you’re experiencing. Once a diagnosis has been made, we talk about it and discuss the next steps, which may include both established treatment options and newer treatments available only in clinical trials. Sometimes no treatment is needed. I want you to leave with a clear understanding of your diagnosis, an appropriate plan of care and the comfort that comes from being supported by an experienced team of doctors.

Provider background

Specialties: Medical Oncology, Hematology

Area of clinical practice

Hematologic malignancies, non-malignant hematology

Hematology oncology

My clinical and research interests include nonmalignant blood disorders, leukemia, lymphoma, multiple myeloma and myelodysplastic syndrome. I’m a board-certified hematologist at Fred Hutch and a UW associate professor of hematology and medicine. As an expert who studies and treats rare diseases, I work with a broad range of patients, some of whom participate in clinical trials.

My areas of clinical expertise include acquired aplastic leukemia, acute myeloid leukemia, chronic myeloid leukemia, essential thrombocytosis, hairy cell leukemia, Langerhans cell histiocytosis, lymphoproliferative disorder, mastocytosis, myelodysplastic syndrome, myelofibrosis, myeloproliferative syndrome, polycythemia vera and post-transplant lymphoproliferative disorder.

Benign Not cancer. Benign tumors may grow larger but do not spread to other parts of the body. Benign Not cancer. Benign tumors may grow larger but do not spread to other parts of the body. Hematologist A physician who specializes in diseases of the blood and blood-forming tissues. Lymphoma Cancer that begins in the cells of the immune system. There are two basic categories of lymphomas: Hodgkin lymphoma and non-Hodgkin lymphomas. Cancer that begins in cells of the immune system. There are two basic categories of lymphomas. One is Hodgkin lymphoma, which is marked by the presence of a type of cell called the Reed-Sternberg cell. The other category is non-Hodgkin lymphomas, which includes a large, diverse group of cancers of immune system cells. Non-Hodgkin lymphomas can be further divided into cancers that have an indolent (slow-growing) course and those that have an aggressive (fast-growing) course. These subtypes behave and respond to treatment differently. Both Hodgkin and non-Hodgkin lymphomas can occur in children and adults, and prognosis and treatment depend on the stage and the type of cancer.

Diseases treated

Education, experience and certifications
Undergraduate Degree
Indiana University Bloomington
Medical Degree
Indiana University School of Medicine
Indiana University School of Medicine, Internal Medicine
University of Washington, Hematology
Board Certification
Hematology, 2000, 2010; Internal Medicine, 1998, 2019, American Board of Internal Medicine


“Dr. Hendrie juggles multiple complex roles as a physician, a mentor and medical director for the inpatient oncology service. He does all of them exceptionally well while always putting his individual patients first. ”
— Colin Godwin, MD


Clinical trials

We make promising new treatments available to you through studies called clinical trials led by Fred Hutch doctors. Many of these trials at Fred Hutch have led to FDA-approved treatments and have improved standards of care globally. Together, you and your doctor can decide if a study is right for you.


Many of our Fred Hutch doctors conduct ongoing research to improve standards of patient care. Their work is evaluated by other doctors and selected for publication to the United States National Library of Medicine, the largest medical library in the world. See scientific papers this Fred Hutch provider has written.

Your care team

At Fred Hutch, you receive care from a team of providers with extensive experience in your disease. Your team includes doctors, a patient care coordinator, a registered nurse, an advanced practice provider and others, based on your needs. You also have access to experts like nutritionists, social workers, acupuncturists, psychiatrists and more who specialize in supporting people with cancer or blood disorders.
Gabrielle A. Zecha, PA-C, MHA
Gabrielle A. Zecha, PA-C, MHA
Physician Assistant
Advanced Practice Provider
Registered nurse (RN)
Registered nurse (RN)
Your nurse manages your care alongside your doctor and assists with care procedures and treatments.
Patient care coordinator
Patient care coordinator
Your patient care coordinator works closely with you and your doctor and serves as your scheduler.


Fred Hutch accepts most national private health insurance plans as well as Medicare. We also accept Medicaid for people from Washington, Alaska, Montana and Idaho. We are working to ensure that everyone, no matter what their financial situation, has access to the care they need.

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