Matthew Triplette, MD, MPH

Medical Director, Lung Cancer Early Detection and Prevention Clinic
Fred Hutch
Assistant Professor, Division of Pulmonary, Critical Care and Sleep Medicine
University of Washington School of Medicine
Assistant Professor, Clinical Research Division
Fred Hutch
“I believe that the safe, complex and state-of-the-art care that our patients deserve is most effectively delivered through a team-based approach.”
— Dr. Triplette
Why do you practice oncology?

Working in healthcare allows me to pursue a passion for science and discovery to improve overall population health for the future while also developing individual therapeutic relationships to help patients and families deal with disease with the best technology of today. Cancer patients and their families show the best of humanity. Their ability to face their illnesses with courage and dignity constantly inspires me. My primary research is to better understand how best to utilize lung cancer screening to save the most lives and make this an effective service for eligible patients. I also study lung disease and lung cancer in immune-suppressed patients, such as persons living with HIV, to understand unique risk factors in these populations. In the realm of lung cancer where we diagnose most cancers in advanced and incurable stages, I hope improvements in screening and detection lead to more early diagnoses and improved survival. Outside of work, I love spending time outdoors in and around Seattle. I enjoy hiking, biking, running and skiing. I love to travel (particularly for the food!) I also enjoy hanging out with my family and my pets.  

Screening Checking for disease when there are no symptoms. Because screening may find diseases at an early stage, there may be a better chance of curing the disease Checking for disease when there are no symptoms. Because screening may find diseases at an early stage, there may be a better chance of curing the disease. Examples of cancer screening tests are the mammogram (for breast cancer), colonoscopy (for colon cancer) and Pap and HPV tests (for cervical cancer). Screening can also include a genetic test to check for a person’s risk of developing an inherited disease.

Provider background

Specialty: Pulmonology

Area of clinical practice

High risk prevention, thoracic cancers

Lung cancer early detection

When I care for patients in the intensive care unit and in pulmonary clinics at the University of Washington and Seattle Cancer Care Alliance, I am continuously amazed by our nurses, housestaff, advanced practice providers, technicians and other staff members who work together to provide comprehensive and compassionate care for our patients. My goal is to provide leadership in patient care worthy of their efforts.

Thoracic Having to do with the chest.

Diseases treated

Education, experience and certifications
Medical Degree
University of North Carolina, Chapel Hill
University of California, San Francisco
University of Washington
Board Certification
Internal Medicine, 2014; Pulmonary Disease, 2017; Critical Care Medicine, 2018, American Board of Internal Medicine
MPH, University of North Carolina, Chapel Hill


Why It’s So Hard for Indigenous People to Quit Smoking
Why It’s So Hard for Indigenous People to Quit Smoking

Nina McEachem picked up smoking as a teen living in Ketchikan, Alaska. She had entered foster care at age 11 after her mother died of leukemia and her father, a school janitor, was overwhelmed caring for five children. In her community—McEachem has both Alaska Native and Aleutian heritage—most people that she knew smoked. Her father was a heavy smoker and experienced a heart attack when McEachem was 19; before that, she said she and her eighth-grade friends smoked behind the school.

How to set up a lung cancer screening program
How to set up a lung cancer screening program

Lung cancer is the leading cause of death in the U.S. and highly treatable when caught early. But less than 15% of people at high risk for lung cancer receive potentially life-saving screening.


Clinical trials

We make promising new treatments available to you through studies called clinical trials led by Fred Hutch doctors. Many of these trials at Fred Hutch have led to FDA-approved treatments and have improved standards of care globally. Together, you and your doctor can decide if a study is right for you.


Many of our Fred Hutch doctors conduct ongoing research to improve standards of patient care. Their work is evaluated by other doctors and selected for publication to the United States National Library of Medicine, the largest medical library in the world. See scientific papers this Fred Hutch provider has written.

Your care team

At Fred Hutch, you receive care from a team of providers with extensive experience in your disease. Your team includes doctors, a patient care coordinator, a registered nurse, an advanced practice provider and others, based on your needs. You also have access to experts like nutritionists, social workers, acupuncturists, psychiatrists and more who specialize in supporting people with cancer or blood disorders.
Maggie K.  Guerriero, MSN, RN, ARNP
Maggie K. Guerriero, MSN, RN, ARNP
Advanced Registered Nurse Practitioner
Advanced Practice Provider
Registered nurse (RN)
Registered nurse (RN)
Your nurse manages your care alongside your doctor and assists with care procedures and treatments.
Patient care coordinator
Patient care coordinator
Your patient care coordinator works closely with you and your doctor and serves as your scheduler.


Fred Hutch accepts most national private health insurance plans as well as Medicare. We also accept Medicaid for people from Washington, Alaska, Montana and Idaho. We are working to ensure that everyone, no matter what their financial situation, has access to the care they need.

For providers