Jonathan J. Chen, MD, PhD

Physician
Fred Hutch
Assistant Professor, Division of Radiation Oncology
University of Washington School of Medicine
Attending Physician
UW Medicine
Assistant Professor, Clinical Research Division
Fred Hutch
Specialty:
Radiation Oncology
“Many people arrive at their first appointment feeling anxious and unsure what to expect. It’s heartening to see the transformation they go through over the course of the visit.”
— Dr. Chen
Why did you decide to become a doctor?

A mentor in college actually discouraged me from becoming a doctor. She said it required so many sacrifices that I should only do it if I couldn’t see myself doing anything else. So, for a few years, I pursued a career in biotech. While working at my first job after college, I volunteered at a free STD clinic at the local hospital. There, I witnessed the impact that doctors could make — and that clinched it for me. I realized that I truly couldn’t see myself doing anything else. The next thing I knew, I was applying to medical school.

Jonathan Chen, MD
What is your approach to care?

I strive to live my life by the Golden Rule, and the same applies to the way I approach being a physician. If I were a patient, how would I want to be treated? How would I want to be spoken to? What things would I appreciate? I try to treat each person with compassion and patience, offering the personal attention that I would want a doctor to give me or my family. My favorite memories of interactions with patients are often initial consultations. Many people arrive at that first appointment feeling anxious, scared and uncertain. It’s heartening to see the transformation they go through over the course of the visit.

Provider background

Specialty: Radiation Oncology

Area of clinical practice

Genitourinary cancers, kidney cancer

Genitourinary cancers and ocular melanoma

I am a board-certified radiation oncologist who specializes in caring for patients with ocular melanoma, the most common type of eye tumor, and genitourinary cancers (GU), which affect the urinary tract and male reproductive system. My expertise includes using proton therapy, a type of targeted radiation therapy that minimizes radiation exposure to healthy tissue. At UW Medicine, I research ways to improve treatments for GU cancers, such as prostate cancer, as well as ocular melanoma. Prior to joining Fred Hutch, I completed a PhD in pharmacology and served as chief resident at New York-Presbyterian Hospital.

Melanoma Cancer that begins in the melanocytes (cells that make the pigment melanin). It may begin in a mole (skin melanoma), but it can also begin in other pigmented tissues, such as the eye or the intestines. Oncologist A physician who has special training in diagnosing and treating cancer. Some oncologists specialize in a particular type of cancer treatment, such as treating cancer with radiation. A physician who has special training in diagnosing and treating cancer. Some oncologists specialize in a particular type of cancer treatment. For example, a radiation oncologist specializes in treating cancer with radiation. Radiation therapy The use of high-energy radiation from X-rays, gamma rays, neutrons, protons and other sources to kill cancer cells and shrink tumors. The use of high-energy radiation from x-rays, gamma rays, neutrons, protons and other sources to kill cancer cells and shrink tumors. Radiation may come from a machine outside the body (external-beam radiation therapy), or it may come from radioactive material placed in the body near cancer cells (internal radiation therapy or brachytherapy). Systemic radiation therapy uses a radioactive substance, such as a radiolabeled monoclonal antibody, that travels in the blood to tissues throughout the body.

Diseases treated

Education, experience and certifications
Undergraduate Degree
Stanford University
Medical Degree
Weill Cornell Medical College
Residency
New York-Presbyterian/Weill Cornell Medical Center, Radiation Oncology
Other
PhD, Pharmacology, Weill Cornell Graduate School
Board Certification
Radiation Oncology
Languages
English

Stories

Celebrating 10 Years of Proton Therapy in the Northwest; Proton Therapy Clinical Trials; Newest Team Coordinator, Jenny Dang
Celebrating 10 Years of Proton Therapy in the Northwest; Proton Therapy Clinical Trials; Newest Team Coordinator, Jenny Dang

March 2023 marks the 10th Anniversary of the proton therapy facility. Thank you to all our dedicated patients, doctors and staff who've made this place what it is today. Also, learn more about the ongoing clinical trials our doctors are conducting and meet our newest team coordinator. 

Oncology nurse supports her husband through proton therapy for prostate cancer treatment
Oncology nurse supports her husband through proton therapy for prostate cancer treatment

In December of 2020, Terry Wyman, who is currently 73 years old and considered part of a high-risk age group for prostate cancer, received a Prostate-Specific Antigen (PSA) test during his annual check-up. His doctor had noted Terry had elevated PSA levels, a potential indicator of prostate cancer.

Research

Clinical trials

We make promising new treatments available to you through studies called clinical trials led by Fred Hutch doctors. Many of these trials at Fred Hutch have led to FDA-approved treatments and have improved standards of care globally. Together, you and your doctor can decide if a study is right for you.

Study ID:
NCT04423211
Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Using PET/CT Imaging
Complete title
Phase III Study of Local or Systemic Therapy INtensification DIrected in Prostate CAncer Patients with Post-ProstaTEctomy Biochemical Recurrence (INDICATE)

Publications

Many of our Fred Hutch doctors conduct ongoing research to improve standards of patient care. Their work is evaluated by other doctors and selected for publication to the United States National Library of Medicine, the largest medical library in the world. See scientific papers this Fred Hutch provider has written.

Press

Our providers are often asked to give their medical expertise for press and news publications. Read articles by or about this Fred Hutch provider.

Your care team

At Fred Hutch, you receive care from a team of providers with extensive experience in your disease. Your team includes doctors, a patient care coordinator, a registered nurse, an advanced practice provider and others, based on your needs. You also have access to experts like nutritionists, social workers, acupuncturists, psychiatrists and more who specialize in supporting people with cancer or blood disorders.
Registered nurse (RN)
Registered nurse (RN)
Your nurse manages your care alongside your doctor and assists with care procedures and treatments.
Patient care coordinator
Patient care coordinator
Your patient care coordinator works closely with you and your doctor and serves as your scheduler.

Insurance

Fred Hutch accepts most national private health insurance plans as well as Medicare. We also accept Medicaid for people from Washington, Alaska, Montana and Idaho. We are working to ensure that everyone, no matter what their financial situation, has access to the care they need.

For providers