A Tradition of Lifesaving Treatment
Bone marrow transplantation—the most effective treatment for many blood cancers—is one of the greatest success stories in cancer treatment. Doctors at the Fred Hutchinson Cancer Research Center—including co-founder and Nobel Laureate Dr. E. Donnall Thomas—pioneered and perfected this lifesaving treatment. The Fred Hutchinson Transplant Program at Seattle Cancer Care Alliance remains the recognized leader in bone marrow transplantation for people with lymphoma, leukemia, and other blood diseases. Our physicians continue to advance the knowledge and use of bone marrow transplantation, expanding and improving treatment options for an increasingly broad patient population.
Most Experienced, Best Outcomes
Doctors at the Fred Hutchinson Transplant Program at Seattle Cancer Care Alliance have performed more than 14,000 bone marrow transplants—more than any institution in the world. The diseases we treat most often are lymphoma, multiple myeloma, and acute myelogenous leukemia, but our doctors are also advancing the use of bone marrow transplants for additional cancers, bone marrow deficiencies, inborn errors of metabolism, and immune disorders. Our program consistently ranks among the country’s top transplant centers in one-year survival rates.
Transplants for a Wide Range of Patients
Our Alternative Donor Program is one of a handful in the United States that provides opportunities for nearly any patient to receive a transplant. People who can’t find matched unrelated donors now have several alternatives. For these patients, we offer transplantation using a haploidentical donor, unrelated cord blood donor, or mismatched unrelated donor. Using current protocols, outcomes of these transplants can be very similar to those using matched donors, including the incidences of acute or chronic graft-versus-host disease.
Experts in Cord Blood and Mini-transplant
The Fred Hutchinson Transplant Program’s Dr. Colleen Delaney is pioneering treatment with transplants of cord blood stem cells. Delaney and her colleagues have devised a technique that multiplies the number of stem cells in cord blood 150 times. More stem cells means faster engraftment, which lessens the risk of life-threatening infections that once stymied the use of this treatment option in adults.
Dr. Paul O’Donnell and colleagues are pioneering treatment with transplants of bone marrow from haploidentical (half-matched) family donors. With this approach, parents, children and most siblings are potential donors for family members with malignant or non-malignant blood disorders. The key to successful transplantation is single administration of a low cost chemotherapy drug after transplantation.
For patients who are unable to withstand the rigors of conventional blood stem-cell transplant, our program offers a less toxic technique: mini-transplants. More than a decade ago, our Dr. Rainer Storb and his colleagues developed the technique, offering new hope for older adults and younger patients, including children, who are unable to tolerate high-dose conditioning.
Drs. Delaney, O’Donnell and Storb are part of a program with a proud tradition in clinical research. We are dedicated to bringing promising new treatments to people quickly. For bone marrow transplant patients, that means access to more treatment options, including the chance to participate in ongoing clinical studies.
One-of-a-kind Follow-up and Access
Our dedication to patients does not end with transplantation. The Fred Hutchinson Transplant Program has the only dedicated long-term followup program in the country. Our Adult Clinical Care Long-Term Follow-Up Program, under the direction of Dr. Mary E. Flowers, provides lifelong monitoring, support, and care for patients after bone marrow or stem cell transplant. Our goals are to maintain and improve health, and to care for present and future physical and emotional needs. After discharge, our medical staff conducts telephone consultations with patients and their health care providers to manage potential complications quickly and answer questions as they arise. No matter where they live, patients and their doctors are always in touch with Fred Hutchinson transplant experts—for life.