Any patient with recurrent prostate cancer
About the FACBC PET/CT Registry at Seattle Cancer Care Alliance
Trial Contact Email
Prostate cancer is a disease that is unlike most malignancies because it offers a sensitive biomarker of detection, prostate-specific antigen (PSA). As a result of PSA, we are able to diagnose the disease earlier. Patients with high risk-localized prostate cancer undergo standard of care treatment with either radical prostatectomy or external beam radiation combined with androgen deprivation therapy (ADT). However, not all patients are cured with surgery or radiation, and these patients eventually develop biochemically-recurrent (BCR) prostate cancer with elevations in PSA. There is no definitive standard of care for these patients and treatments range from salvage local therapy to androgen deprivation therapy to observation until radiographically-detectable metastasis or symptoms. With next generation PET imaging, like fluciclovine (Axumin) PET imaging, we are now able to detect recurrent prostate cancer at very low PSA levels. However, what should be done once disease is detected? Should we offer ADT or should we intensify metastasis directed therapy with more surgery or radiation? These are questions that are yet unanswered for the field. Hence, we have started a registry that will enroll patients with recurrent prostate cancer who are interested in undergoing PET imaging with fluciclovine. We will determine the purpose for obtaining fluciclovine PET imaging, the results of the study, what actions are taken in response to those results and what the long-term outcomes are for each patient. Any patient with recurrent prostate cancer with plans to undergo fluciclovine PET imaging will be eligible. For more information or to enroll your patient, please contact registry coordinators Nate Conrad (firstname.lastname@example.org) and Katerina Alexander (email@example.com).
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