Dr. Alessandro Fichera gives an overview of colon cancer. The majority of colon cancer cases develop from small polyps that become larger and then cancerous. Other pathways are being identified stemming from flat lesions or associated with inflammatory bowel disease, which are more difficult to detect. Regular colonoscopies are vital for early detection, and should occur by age 50 in the general population, or age 40 or earlier by those with a family history or genetic predisposition. The latest advances in treatment for colon cancer include the ability to see better with endoscopy, more effective medical and radiation treatments, and minimally invasive surgery being as effective as open surgery. The five-year cure rate for stage I cancers are 90%, and stage III as high as 70-75%. The key to success is working with a multidisciplinary team and getting the best treatment the first time.