Text Size A A

E-Mail to a Friend






secret  Click to Play Audio


Biological and Targeted Therapies

Biological and Targeted Therapies

Dr. VK Gadi is an oncologist who specializes in the treatment of breast cancer. In this video, Dr. Gadi explains how biologic or targeted therapies are designed to to go after specific vulnerabilities that are unique to the cancer. One therapy that Dr. Gadi is particularly excited about is the use of Herceptin for patients who have HER2-positive breast cancer. Herceptin is an monoclonal antibody which binds to the HER2 protein on the outside of a cancer cell. Once bound, it initiates a series of events that lead to the destruction of the cancer cell.

Related Videos

Breast Cancer Biology, Stages, and Types

Dr. Larissa Korde provides an overview of breast cancer biology, stages, and types. Breast cancer is the growth of abnormal cells in breast. The stages of development are hyperplasia, atypical hyperplasia, non-invasive cancer or carcinoma in situ, and finally invasive cancer. Dr. Korde explains the stages of breast cancer, ranging from Stage 0, a non-invasive cancer, to Stage 4, a cancer that has spread to other organs. Other factors that an oncologist will look at are the receptors that the cancer expresses. Two hormone receptors are estrogen and progesterone, which is treated with hormone therapy. Another receptor is HER2, which treated with HER2 targeted therapy. Triple Negative is a subtype of breast cancer that does not express any of the latter three receptors and is generally treated with chemotherapy. Inflammatory breast cancer is a rare, but aggressive cancer invading the skin tissue

Breast Cancer Care Team

In this video, Dr. VK Gadi describes the five core disciplines involved in managing breast cancer. In general, there are two doctors that you don't meet very often: they are the "what is it?" and "where is it?" doctors--your pathologist and radiologist. And then there are the "doing doctors." The two that go together, the surgeon and the radiation therapist are responsible for the breast and lymph nodes to make sure that whatever disease was once there is completely annihilated by either removing it (by surgery) or zapping it (by radiation). And finally there's the medical oncologist who comes in to eliminate whatever stray cancer cells that may have found their way to other parts of the body.

Breast Cancer Surgery

Dr. Sara Javid Discusses Surgery Options for Breast Cancer Patients There?s a one in eight chance that a woman will have breast cancer in her lifetime. Most who do undergo some type of surgery to remove it. One option available is a lumpectomy, where only the tumor is removed, rather than the entire breast. This is typically followed by a course of radiation to the breast. Dr. Sara Javid, Surgical Oncologist at SCCA, states that after 25 years of follow up, we now know that this procedure is equally safe in terms of survival and recurrence risk of cancer in the breast. SCCA uses a multi disciplinary team approach to treating patients. This gives patients the full picture up front of what to expect and what options are available to them, empowering them to make choices as they move forward with their breast cancer treatment at SCCA.

Breast Cancer Risk Factors and Screening with Dr. Larissa Korde

Breast Cancer Risk Factors and Screening Breast cancer is the second most common type of cancer in women. Knowing your risk factors and getting screened early gives you a better chance for a cure. Age and family history are the two best indicators for risk of breast cancer that cannot be changed. Having a number of family members with breast cancer is also an indicator of genetically inherited types of breast cancer. The top 3 things that influence breast cancer risk that can be changed are diet, weight and physical activity.