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Clinical Trials Monthly - January 2011

SCCA's Alternative Donor Program

This month we are highlighting Seattle Cancer Care Alliance’s Alternative Donor Program for bone marrow transplantation.This program removes barriers to unmatched transplants. Fully 35 percent of people who need a bone marrow transplant don’t have a matched sibling donor, or even a matched unrelated donor. That leaves them looking for alternatives. SCCA’s Alternative Donor Program provides opportunities for almost any patient to be a candidate for a transplant.

Alternative Donor Trials

Nonmyeloablative HCT for Hematologic Malignancies using Related, HLA-Haploidentical Donors (FHCRC-2372)
Nonmyeloablative Hematopoietic Cell Transplantation (HCT) for Patients with Hematologic Malignancies using Related, HLA-Haploidentical Donors: A Phase II trial of Peripheral Blood Stem Cells (PBSC) as the Donor Source.

Investigator: Paul O'Donnell, MD, PhD

I 131 Monoclonal Antibody BC8, Chemotherapy, TBI, and a Donor Bone Marrow Transplant for Advanced Acute Leukemia MDS (FHCRC-2186)
Hematopoietic Bone Marrow Transplantation for Patients with High-Risk Acute Myeloid Leukemia (AML), Acute Lymphoblastic Leukemia (ALL), or Myelodysplastic Syndrome (MDS) using Related HLA-Mismatched Donors: A Trial Using Radiolabeled Anti-CD45 Antibody Combined with Immunosuppression Before and After Transplantation.

Investigator: John Pagel, MD

Unrelated Donor Cord Blood Transplant w/Reduced-intensity Preparative Regimen (FHCRC-2239)
Transplantation of Unrelated Donor Umbilical Cord Blood in Patients with Hematological Malignancies Using a Reduced-intensity Preparative Regimen. SCCA Investigator: Colleen Delaney, MD.

Fludarabine, Cyclophosphamide + TBI Followed by Cord Blood SCT (FHCRC-2044)
A Pilot Study to Evaluate the Co-infusion of Ex Vivo Expanded Umbilical Cord Blood Progenitors with an Unmanipulated Cord Blood Graft in Patients Undergoing Umbilical Cord Blood Transplantation for Hematologic Malignancies.

Investigator: Colleen Delaney, MD

Transplantation Consultation

If you want to discuss treatment options for your patients with a physician, please call our intake office at (206) 288-SCCA (7222) or (800) 804-8824. Ask to speak to the physician transplant specialist or clinical coordinator from Fred Hutchinson Cancer Research Center.

Adult Bone Marrow Transplant News

The SCCA Adult Bone Marrow Transplant News is a publication presenting the latest information on bone marrow transplant research at SCCA, providing up-to-date information for all health care professionals caring for transplant patients.

Pediatric Bone Marrow Transplant News

Read about important outcomes research at the Fred Hutch that may benefit your patients.

Clinical Trials Monthly

Each issue of Clinical Trials Monthly highlights several of the more than 200 clinical trials that are currently recruiting patients at SCCA.

The Leading Edge Newsletter

Each quarterly Leading Edge newsletter will highlight a new topic to give you the latest news on leading-edge therapies that SCCA physicians are offering.