Shwachman-Diamond syndrome (SDS) is an inherited condition that can affect the bone marrow, pancreas, skeletal system, and other organ systems. Children with this disease typically have a shortage of neutrophils (a condition called neutropenia) which makes them more prone to pneumonia, ear infections, and skin infections. SDS can also lead to decreased numbers of red blood cells, called anemia, or decreased numbers of platelets, called thrombocytopenia. A gene mutation in a majority of patients recently discovered reveals new information about the molecular make-up and progression of this disorder.
Outstanding Care Team
The medical team at Seattle Children's, a founding organization of Seattle Cancer Care Alliance, has a long history of successfully caring for children and teens who have Shwachman-Diamond syndrome. These renowned specialists work together to treat this disorder and improve your child's quality of life.
Medical therapy for SDS is provided at Seattle Children's. If your child's health-care team determines that the best course of action is a bone marrow transplant, your child will receive this treatment through Seattle Cancer Care Alliance, ranked first in outcomes in a four-year study by the National Marrow Donor Program (NMDP) that measured one-year survival rates of patients among 122 transplant centers in the United States.