SCID Overview
Seattle Cancer Care Alliance brings together the leading research teams and cancer specialists of Fred Hutch, Seattle Children's, and UW Medicine. One extraordinary group whose sole mission is the pursuit of better, longer, richer lives for our patients. Learn More


Severe combined immunodeficiency (SCID) is a serious medical condition. Children with SCID lack virtually all immune protection against bacteria, viruses, and fungi and are prone to repeated and persistent infections that would not normally cause illness in a person with a normal immune system.  In someone with SCID, these infections can be very serious or life-threatening. SCID is estimated to occur in approximately 1 out of every 50,000 to 100,000 births.

The medical team at Seattle Children's, a parent organization of Seattle Cancer Care Alliance, has a long history of successfully caring for children and teens who have SCID. Renowned specialists from Children's and SCCA work together to improve your child's quality of life and conquer SCID.

Standard therapy for SCID is provided at Seattle Children's. If your child's health-care team determines that the best course of action is a bone marrow transplant, your child will receive this treatment through Seattle Cancer Care Alliance.

Success Rates

If your condition requires a bone marrow transplant, you should know that the Fred HutchTransplant program at SCCA was ranked first in outcomes in a four-year study by the National Marrow Donor Program (NMDP) that measured one-year survival rates of patients among 122 transplant centers in the United States. The Hutch pioneered the use of bone-marrow transplants as a treatment for blood diseases over 40 years ago. Since then thousands of patients with leukemia have come from around the world to receive bone marrow transplants at SCCA. Bone-marrow transplants have transformed leukemia and related cancers, once thought incurable, into highly treatable diseases with survival rates as high as 80 percent.