Juvenile Idiopathic Arthritis (JIA)

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Our Expertise

Patients with autoimmune diseases may be seen at Seattle Cancer Care Alliance, Seattle Children’s, or UW Medical Center.

Fred Hutchinson Cancer Research Center (Hutchinson Center) along with Seattle Children’s is taking the lead on several fronts in treating autoimmune diseases, such as juvenile rheumatoid arthritis. Both organizations have several clinical trials underway using bone marrow (hematopoietic stem cell) transplantation to treat severe autoimmune diseases.

If your child or teenager needs a bone marrow transplant, SCCA is the best place to receive this life-saving treatment. The Hutchinson Center pioneered the use of bone marrow transplants over 40 years ago as a treatment for leukemia. Since then thousands of patients have come from around the world to receive bone marrow transplants at SCCA for cancer and autoimmune diseases.

The Hutchinson Center Transplant Program at SCCA was ranked first in outcomes in a four-year study by the National Marrow Donor Program (NMDP) that measured one-year survival rates of patients among 119 transplant centers in the United States.

Genetic Research

The Hutchinson Center is also leading a global team to accelerate the investigation of immune-related genes. A cluster of nearly 220 genes known as the human leukocyte antigen (HLA) gene complex holds clues to these and other medical issues. In search of answers, the National Institutes of Health launched a $20 million initiative in 2001 to catalog the HLA gene complex. The effort among 200 laboratories in more than 70 countries is lead by Hutchinson Center's Dr. John Hansen. The group will set up a centralized HLA gene database. For patients, the benefits include finding better matches for bone marrow transplant patients.