Diamond-Blackfan Anemia (DBA)

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Diamond-Blackfan anemia (DBA) is a rare disease that is characterized by a shortage of red blood cells due to decreased production by the bone marrow.  Platelets and white blood cell counts are typically normal. Some patients with DBA have malformed thumbs, or cleft lip or palate, receding chin, kidney abnormalities, or heart abnormalities, and may be short in stature. Some patients have no apparent clinical signs of this disease other than anemia.

Most patients will be diagnosed within the first year of life. However, some adults have also been diagnosed.

Outstanding Care Team

DBA is a rare disease and not well understood, which makes treating it challenging. The medical team at Seattle Children's, a parent organization of Seattle Cancer Care Alliance, has a long history of successfully caring for children and teens with DBA. These renowned specialists work together to improve your child's quality of life and conquer this disease.

Medical therapy for DBA is provided at Seattle Children's. If your child's health-care team determines that the best course of action is a bone marrow transplant, your child will receive this treatment through Seattle Cancer Care Alliance, ranked first in outcomes in a four-year study by the National Marrow Donor Program (NMDP) that measured one-year survival rates of patients among 122 transplant centers in the United States.