If you have signs or symptoms that could be from uterine sarcoma (or another problem with your reproductive organs), your doctor will probably start by doing a general physical exam and then a pelvic exam.

To diagnose uterine sarcoma, doctors have to remove a small sample of tissue from your uterus and look at the cells under a microscope. Seattle Cancer Care Alliance has a dedicated pathologist who specializes in the diagnosis of gynecologic cancers.

Endometrial Biopsy

As part of your work-up, your doctor may do an endometrial biopsy. The doctor inserts a thin, flexible, straw-like tube into your uterus through your cervix and scrapes or suctions out a small amount of endometrium so a pathologist can examine the cells for cancer.

Dilation and Curettage

Dilation and curettage (D&C) is another way your doctor can get a sample of cells from inside your uterus. A narrow instrument called a dilator is inserted into your cervix to open it. Next the doctor uses a spoon-like tool called a curette to scrape some tissue from inside your uterus for examination.

Imaging Studies

The only way to tell whether you have uterine sarcoma is to examine samples of tissue. In certain situations, your doctor may also want you to have imaging studies to get more information, such as whether your cancer has spread. These might include an X-ray, ultrasound, computed tomography (CT) scan, and magnetic resonance imaging (MRI) scan. 


American Cancer Society
National Cancer Institute
National Comprehensive Cancer Network