Infections are the most common symptom for this disease. Children often require hospitalization and receive intravenous antibiotics for their infections.
Severe neutropenia can lead to the development of bacterial, fungal, or mixed infections which can become life threatening.
Treatment for severe congenital neutropenia in children usually begins with recombinant human granulocyte colony-stimulating factor (GCSF). However, bone marrow transplant is the only curative treatment for this disease.
Children who develop leukemias may also be treated wtih bone marrow transplantation.