Blood Disorders

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Blood Disorders


Amyloids are abnormal proteins usually produced in your bone marrow that can be deposited in any tissue or organ. Amyloidosis is a rare and potentially fatal disease that occurs when these proteins build up.


Anemia (uh-NEE-me-eh) is a condition in which a person’s blood has a lower than normal number of red blood cells, or those cells don’t have enough hemoglobin, the iron-rich protein that gives blood its red color and carries oxygen from the lungs to the rest of the body.

Essential thrombocythemia

Essential thrombocythemia is also called primary thrombocythemia, terms to describe when a high platelet count occurs alone; Sometimes called idiopathic thrombocythemia.

Fanconi anemia

Fanconi anemia (FA) is a rare, inherited blood disorder that causes your bone marrow to stop making enough new blood cells for your body to work normally.

Gaucher Disease

Gaucher (pronounced "Go-Shay") disease is a genetic disorder caused by deficiency of the enzyme, glucocerebrosidase. This deficiency causes a fatty substance to accumulate in certain body tissues such as the spleen, liver, and bone marrow.


Hemochromatosis is an inherited disease in which too much iron builds up in your body. It is one of the most common genetic diseases in the United States.

Hemolytic anemia

Hemolytic anemia is a rare form of anemia. In this disease, red blood cells are destroyed and removed from the bloodstream prematurely.


Hemophilia is a bleeding disorder caused by a deficiency in one of two blood clotting factors: factor VIII or factor IX. Symptoms can range from very mild, which may go undiagnosed, to severe.


Hypereosinophilia or Hypereosinophilic Syndrome, is a rare blood disorder where people have a marked increase in eosinophils - a type of white blood cell - in their bloodstream.

Idiopathic thrombocytopenic purpura

Platelets are what help bleeding stop by clotting and sealing small cuts or breaks. Idiopathic means that the cause of the disease or condition is not known. Thrombocytopenic means there is a lower-than-normal number of platelets in the blood. Purpura are purple bruises caused by bleeding under the skin.

Inherited Bone Marrow Failure Syndromes

The IBMFS are a group of rare inherited diseases with varying defects in the production of red blood cells, white blood cells, and/or platelets leading to low blood counts.

Iron-Deficiency Anemia

Iron-deficiency anemia is the most common cause of anemia worldwide. It results from a decreased intake of iron or excess loss of iron.

Langerhan Cell Histiocytosis (LCH)

Langerhan cell histiocytosis is a rare blood disease that is caused by an excess of white blood cells called histiocytes, which cluster together and can attack the skin, bones, lung, liver, spleen, gums, ears, eyes, and/or the central nervous system.


Leukopenia is the medical term for low white blood cell count. Infections, such as viral infections and HIV, autoimmune disorders, such as lupus, certain medications, (chemotherapy and some antibiotics), radiation therapy, and bone marrow diseases, such as leukemia or myelodysplastic syndromes, can lead to leucopenia.


Mastocytosis is a group of rare disorders caused by the presence of too many mast cells, or (mastocytes), which are part of the immune system.


Myelofibrosis (also referred to as agnogenic myeloid metaplasia or idiopathic myelofibrosis) is a serious bone marrow disorder that disrupts your body's normal production of blood cells, which causes extensive scarring in your bone marrow.

Myeloproliferative disorders

In myeloproliferative disorders too many blood stem cells develop into one or more types of blood cells. The disorders usually get worse slowly as the number of extra blood cells increases.

Pernicious Anemia

Pernicious anemia is low red blood cell counts due to low levels of vitamin B12.

Polycythemia vera

Polycythemia vera is a disease where too many red blood cells are made in the bone marrow, which makes the blood thick. White blood cells and platelets may also increase and these extra blood cells tend to collect in the spleen causing it to swell.


Porphyria is a group of different disorders caused by abnormalities in the chemical steps leading to the production of heme, a substance that is important in the body. The largest amounts of heme are in the blood and bone marrow, where it carries oxygen. Heme is also found in the liver and other tissues.

Sickle Cell Anemia

Sickle cell anemia is a serious inherited condition in which the body makes an abnormal type of hemoglobin which causes red blood cells to become “c-shaped,” like a sickle.


Thalassemias are inherited blood disorders that cause the body to make fewer healthy red blood cells and less hemoglobin than normal. Mild or severe anemia can also be present in people with thalassemias.


Thrombocytopenia is a condition in which your blood has a low number of platelets, the blood agents that are responsible for clotting to stop any bleeding that could happen if a blood vessel is damaged.


Thrombocytosis and thrombocythemia are conditions in which your blood has a high number of platelets, also called thrombocytes, because a clot is also called a thrombus. When another disease or condition causes a high platelet count, the term "thrombocytosis" is preferred, or secondary or reactive thrombocytosis.

Thrombophlebitis (Deep vein Thrombosis, DVT)

Deep vein thrombosis is a blood clot that forms in a vein deep in the body. Blood clots occur when blood thickens and clumps together. These occur most often in the lower leg or thigh but they can occur in other parts of the body as well and can result from several things, including damage that occurs to a vein's inner lining from injuries caused by physical, chemical, or biological factors like, inflammation, or immune response.

Thrombotic Thrombocytopenic Purpura (TTP)

Thrombotic thrombocytopenic purpura (TTP) is a rare blood condition that causes blood clots to form in small blood vessels throughout the body, which can cause serious problems if they block blood vessels and limit blood flow to the brain, kidneys, or heart.

Von Willebrand Disease

The von Willebrand factor is a protein that helps blood clot. Von Willebrand disease (VWD) is the most common of all the inherited bleeding disorders, occurring in about 1 out of every 100 to 1,000 people.