Renal Cell Carcinoma
|Closed||Renal Cell Carcinoma||Phase I||NCT01677390|
This is a phase 1, open-label, dose-escalation clinical trial to evaluate the safety of SGN-75 in combination with everolimus in patients with CD70-positive metastatic renal cell carcinoma.
- Diagnosis of metastatic renal cell carcinoma with confirmed CD70 expression
- Previously treated with 1 or 2 tyrosine kinase inhibitors (TKIs)
- Measurable disease
- Eastern Cooperative Oncology Group performance status 0 or 1
- Adequate lung and renal function
- Prior treatment with anti-CD70-directed therapy
- Prior treatment with an mTOR inhibitor
See this trial at ClinicalTrials.gov
Access protocol and consent forms at Fred Hutchinson Cancer Research Center
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