Phase 1 Program

SCCA Clinical Studies: Phase 1 Program

SGN-75 + Everolimus for Metastatic Renal Cell Carcinoma
A Phase 1b, Open-label, Dose-escalation Study to Evaluate the Safety and Tolerability of SGN-75 in Combination With Everolimus in Patients With CD70-positive Metastatic Renal Cell Carcinoma
Status Conditions Phase Study ID
Closed Renal Cell Carcinoma Phase I NCT01677390

This is a phase 1, open-label, dose-escalation clinical trial to evaluate the safety of SGN-75 in combination with everolimus in patients with CD70-positive metastatic renal cell carcinoma.

John A. Thompson, MD
SCCA Phase 1 Program Office 206-288-7551 Refer Patient
Eligibility Criteria (must meet the following to participate in this study)
  • Diagnosis of metastatic renal cell carcinoma with confirmed CD70 expression
  • Previously treated with 1 or 2 tyrosine kinase inhibitors (TKIs)
  • Measurable disease
  • Eastern Cooperative Oncology Group performance status 0 or 1
  • Adequate lung and renal function
Exclusions (conditions that would prevent participation in this study)
  • Prior treatment with anti-CD70-directed therapy
  • Prior treatment with an mTOR inhibitor
  • Last Updated
    November 07, 2013
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    Access protocol and consent forms at Fred Hutchinson Cancer Research Center
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