Clinical Trials

Text Size A A

E-Mail to a Friend






secret  Click to Play Audio


Pediatric Studies

Brain Function in Young Patients Receiving Methotrexate for ALL (COG AALL06N1)
A Study of Neurocognitive Function in Children Treated for ALL. A Group-wide, Non-therapeutic Companion Study to AALL0232 and AALL0434
Status Conditions Phase Study ID
Recruiting Acute Lymphoid Leukemia (ALL) NA COG AALL06N1
NCT00437060
Summary

RATIONALE: Learning about the long-term effects of methotrexate on brain function may help doctors plan cancer treatment.

PURPOSE: This clinical trial is looking at brain function in young patients receiving methotrexate for acute lymphoblastic leukemia.


Investigator
Doug Hawkins, MD
Location    
Seattle Cancer Care Alliance 800-804-8824  
Eligibility Criteria (must meet the following to participate in this study)
Ages Eligible for Study:   1 Year to 17 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

DISEASE CHARACTERISTICS:

  • Diagnosis of acute lymphoblastic leukemia
  • Enrolled on COG-AALL0434 or COG-AALL0232
  • No CNS-3 disease

PATIENT CHARACTERISTICS:

  • No known significant neurodevelopmental disability unrelated to cancer diagnosis including, but not limited to, any of the following:

    • Down syndrome
    • Fragile X mental retardation
    • Autism
    • Pervasive developmental disability
    • Seizure disorder
  • Attention-deficit hyperactivity disorder or specific learning disability (e.g., dyslexia) allowed
  • No sensory impairment (e.g., pre-existing uncorrectable vision impairment or deafness)

PRIOR CONCURRENT THERAPY:

  • See Disease Characteristics
  • No cranial radiation therapy
Last Updated
June 03, 2010
See this trial at ClinicalTrials.gov
Access protocol and consent forms at Fred Hutchinson Cancer Research Center
Disclaimer: We update this information regularly. However, what you read today may not be completely up to date.

Please remember:
  • Talk to your health care providers first before making decisions about your health care.
  • Whether you are eligible for a research study depends on many things. There are specific requirements to be in research studies. These requirements are different for each study.