Clinical Trials

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Multiple Myeloma

 

Yttrium Y 90 anti-CD45 monoclonal antibody BC8 + Chemo + TDI before Transplant for Multiple Myeloma (2450)
A Phase I Study of 90Y-BC8-DOTA monoclonal antibody, Fludarabine and TBI Followed by HLA-Matched, Allogeneic Peripheral Blood Stem Cell Transplant for the Treatment of Multiple Myeloma

Investigator: Bill Bensinger, MD;   Conditions: Refractory Multiple Myeloma, Stage I Multiple Myeloma, Stage II Multiple Myeloma, Stage III Multiple Myeloma;    Status: Recruiting;   Study ID: NCT01503242

Lenalidomide + Bortezomib + Dexamethasone for Multiple Myeloma (2477)
A Randomized Phase III Study Comparing Conventional Dose Treatment Using a Combination of Lenalidomide, Bortezomib and Dexamethasone (RVD) to High-Dose Treatment with Peripheral Stem Cell Transplant in the Initial Management of Myeloma in Patients up to 65 Years of Age (IFM/DFCI 2009)

Investigator: Bill Bensinger, MD;   Conditions: Multiple Myeloma;    Status: Recruiting;   Study ID: NCT01208662

BHQ880 for High Risk Smoldering Multiple Myeloma (2482)
A Single-Arm, Open-Label, Phase II Clinical Trial Evaluating Disease Response following Treatment with Intravenous BHQ880, a Fully Human, Anti-Dickkopf1 (DKK1) Neutralizing Antibody in Previously Untreated Patients with High-risk, Smoldering Multiple Myeloma

Investigator: Bill Bensinger, MD;   Conditions: Multiple Myeloma (MM);    Status: Recruiting;   Study ID: NCT01302886

Oral MLN9708 for Relapsed and Refractory Multiple Myeloma (2360)
An Open Label, Dose Escalation, Phase 1 Study Evaluating the Safety and Tolerability of Weekly Dosing of the Oral Form of MLN9708, a Second Generation Proteasome Inhibitor, in Adult patients with Relapsed and Refractory Multiple Myeloma

Investigator: Bill Bensinger, MD;   Conditions: Multiple Myeloma (MM);    Status: Recruiting;   Study ID: NCT00963820

Dose Escalation Study of MFGR1877S for Multiple Myeloma (2422)
An Open-Label, Multicenter, Phase I Trial of the Safety and Pharmacokinetics of Escalating Doses of MFGR1877S in Patients With Relapsed or Refractory t(4;14)-Positive Multiple Myeloma

Investigator: Bill Bensinger, MD;   Conditions: Hematologic Malignancies; Multiple Myeloma (MM);    Status: Recruiting;   Study ID: NCT01122875

Dose Escalation Study of KW-2478 in Combination with Bortezomib for Multiple Myeloma (2401)
An Open-Label, Dose Escalation, Multicenter Phase 1/2 Study of KW-2478 in Combination with Bortezomib in Subjects with Relapsed and/or Refractory Multiple Myeloma

Investigator: Bill Bensinger, MD;   Conditions: Multiple Myeloma;    Status: Closed;   Study ID: NCT01063907

ARRY-520 for Relapsed/Refractory Multiple Myeloma (2402)
A Phase 1/2 Study Of Arry-520 In Patients With Relapsed Or Refractory Multiple Myeloma

Investigator: Bill Bensinger, MD;   Conditions: Multiple Myeloma;    Status: Recruiting;   Study ID: NCT00821249

Carfilzomib, Lenalidomide, and Dexamethasone (CRd) vs Lenalidomide and Dexamethasone (Rd) in Subjects With Relapsed Multiple Myeloma (2419)
A Randomized, Multicenter, Phase 3 Study Comparing Carfilzomib, Lenalidomide, and Dexamethasone (CRd) vs Lenalidomide and Dexamethasone (Rd) in Subjects with Relapsed Multiple Myeloma

Investigator: Bill Bensinger, MD;   Conditions: Relapsed Multiple Myeloma;    Status: Recruiting;   Study ID: NCT01080391