SCCA Clinical Studies: Lung Cancer
Crizotinib (PF-02341066) for NSCLC with Profile Involving ALK Gene (UW09035)
Phase 2, Open-Label Single Arm Study Of The Efficacy And Safety Of PF-02341066 (Crizotinib) In Patients With Non-Small Cell Lung Cancer Harboring A Translocation Or Inversion Event Involving The Anaplastic Lymphoma Kinase (ALK) Gene
| Status | Conditions | Phase | Study ID |
| Closed | Non-Small-Cell Lung Carcinoma | Phase II |
UW09035 NCT00932451 |
Summary
This is a Phase 2 trial that will evaluate the safety and efficacy of PF-02341066 in patients with advanced non-small cell lung cancer with a specific gene profile involving the ALK gene. This trial will allow patients from a Phase 3 trial who received standard of care chemotherapy (Study A8081007) to receive PF-02341066.
|
|
Eligibility Criteria (must meet the following to participate in this study)
| Ages Eligible for Study: | 18 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
Criteria
Inclusion Criteria:
- histologically or cytologically proven diagnosis of non-small cell lung cancer
- positive for the ALK fusion gene (test provided by a central laboratory)
- received pemetrexed or docetaxel from previous Phase 3 trial (A8081007) and discontinued treatment due to Response Evaluation Criterion in Solid Tumors (RECIST)-defined progression
Exclusion Criteria:
- prior treatment with PF-02341066
- received no prior chemotherapy for advanced non-small cell lung cancer
- current enrollment in another therapeutic clinical trial
Last Updated
September 16, 2011See this trial at ClinicalTrials.gov
Access protocol and consent forms at Fred Hutchinson Cancer Research Center
Disclaimer: We update this information regularly. However, what you read today may not be completely up to date.
Please remember:
Please remember:
- Talk to your health care providers first before making decisions about your health care.
- Whether you are eligible for a research study depends on many things. There are specific requirements to be in research studies. These requirements are different for each study.