Clinical Trials

Text Size A A

E-Mail to a Friend






secret  Click to Play Audio


Breast Cancer

 

Pfizer Sutent (6488)
A Phase II Study Evaluating the Safety and Efficacy of Sunitinib Maleate (Sutent) in Combination With Weekly Paclitaxel (Taxol) Followed by Doxorubicin (Adriamycin) and Daily Oral Cyclophosphamide (Cytoxan) Plus G-CSF as Neoadjuvant Chemotherapy for Locally Advanced or Inflammatory Breast Cancer

Investigator: Jennifer Specht, MD;   Conditions: Breast Cancer;    Status: Recruiting;   Study ID: NCT00513695

Trastuzumab Emtansine (T-DM1) for HER2-Positive Breast Cancer (UW11034)
A Phase III Randomized, Multicenter, Two-Arm, Open-Label Trial to Evaluate the Efficacy of Trastuzumab Emtansine Compared With Treatment of Physician's Choice in Patients With HER2 Positive Metastatic Breast Cancer Who Have Received at Least Two Prior Regimens of HER2 Directed Therapy

Investigator: V.K. Gadi, MD, PhD;   Conditions: Breast Cancer;    Status: Recruiting;   Study ID: NCT01419197

Metformin for Early Stage Breast Cancer (SWOG MA.32)
Phase III Randomized Trial of the Effect of Metformin versus Placebo on Recurrence and Survival in Early Stage Breast Cancer

Investigator: Fred Appelbaum, MD;   Conditions: Breast Cancer;    Status: Recruiting;   Study ID: NCT01101438

Chemo w/wo Trastuzumab After Surgery for Invasive Breast Cancer (NSABP B-47)
A Randomized Phase III Trial of Adjuvant Therapy Comparing Chemotherapy Alone (Six Cycles of Docetaxel Plus Cyclophosphamide or Four Cycles of Doxorubicin Plus Cyclophosphamide Followed by Weekly Paclitaxel) to Chemotherapy Plus Trastuzumab (Herceptin) in Women with Node-Positive or High-Risk Node-Negative HER2-Low Invasive Breast Cancer

Investigator: Tanya Wahl, MD;   Conditions: Breast Cancer;    Status: Recruiting;   Study ID: NCT01275677

Combination Chemo w/wo Bevacizumab for Inflammatory or Locally Advanced Breast Cancer (SWOG 0800)
A Randomized Phase II Trial of Weekly Nanoparticle Albumin Bound Paclitaxel (Nab-Paclitaxel) (NSC-736631) With or Without Bevacizumab, Either Preceded by or Followed By Q 2 Week Doxorubicin (A) and Cyclophosphamide (C) Plus Pegfilgrastim (PEG-G) As Neoadjuvant Therapy for Inflammatory and Locally Advanced Her-2/Neu Negative Breast Cancer

Investigator: Fred Appelbaum, MD;   Conditions: Breast Cancer;    Status: Recruiting;   Study ID: NCT00856492

Ampligen w/Vaccine Therapy for Stage II-IV HER2-Positive Breast Cancer (7425)
Phase I-II Study of HER2 Vaccination with poly(I) Poly(C12U) (Ampligen®) as an Adjuvant in Optimally Treated Breast Cancer Patients

Investigator: Lupe Salazar, MD;   Conditions: Breast Cancer;    Status: Recruiting;   Study ID: NCT01355393

Changing vs Maintaining Rx Based on CTC (SWOG-0500)
A Randomized Phase III Trial to Test the Strategy of Changing Therapy Versus Maintaining Therapy for Metastatic Breast Cancer Patients Who Have Elevated Circulating Tumor Cell Levels at First Follow-Up Assessment

Investigator: Frederick Appelbaum, MD;   Conditions: Breast Cancer;    Status: Recruiting;   Study ID: NCT00382018

Early Assessment Challenge Grant (7043)
Imaging Early Response of ER+, HER2- Breast Cancer To Aromatase Inhibitor (AI) Therapy

Investigator: David Mankoff, M.D., PhD ;   Conditions: Breast Cancer;    Status: Recruiting

Whole Breast Irradiation with Hypofractionation versus standard Whole Breast Irradiation (RTOG 1005)
A Phase III clinical trial of Accelerated Whole Breast Irradiation with Hypofractionation plus concurrent boost versus standard Whole Breast Irradiation plus sequential boost for early-stage breast cancer.

Investigator: George Laramore, MD;   Conditions: Breast cancer;    Status: Recruiting;   Study ID: NCT01349322