Clinical Trials

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Brain/Spinal Cord Cancers


Depocyt-Methotrexate trial for Leptomeningeal Metastases (6954)
A Phase II Study of the Combination of High-dose Methotrexate and Intrathecal Liposomal Cytarabine in Patients with Parenchymal and Leptomeningeal Metastases from Breast Cancer

Investigator: Maciej Mrugala, MD, PhD;   Conditions: Stage IV Breast Cancer, Central Nervous System Involvement/Metastases, Leptomeningeal Metastases, Recurrent Breast Cancer, Tumors Metastatic to Brain;    Status: Closed;   Study ID: NCT00992602

Bevacizumab w/wo Radiation Therapy for Recurrent Glioblastoma (RTOG-1205)
Randomized Phase II Trial Of Concurrent Bevacizumab and Re-Irradiation Versus Bevacizumab Alone as Treatment for Recurrent Glioblastoma

Investigator: George E. Laramore, MD;   Conditions: Adult Glioblastoma;    Status: Recruiting;   Study ID: NCT01730950

Radiation Therapy With or Without Temozolomide for Anaplastic Glioma (RTOG 0834)
Phase III Trial On Concurrent and Adjuvant Temozolomide Chemotherapy in Non-1P/19Q Deleted Anaplastic Glioma: The CATNON Intergroup Trial

Investigator: George Laramore, MD, PhD;   Conditions: Brain and Central Nervous System Tumors;    Status: Recruiting;   Study ID: NCT00626990

Imaging Study 7754
Cellular Proliferation Using [18F] fluorothymidine (FLT) Positron Emission Tomography (PET) in Brain Tumors

Investigator: Janet Eary, MD;   Conditions: Brain Tumor;    Status: Recruiting

Imaging Study 21213
Assessing Brain Tumors with [18F] Fluoromisonidazole (FMISO) PET

Investigator: Janet Eary, MD;   Conditions: Brain Tumor;    Status: Recruiting

Imaging Study 7185
Distinguishing Recurrent Glioma From Post-Radiation Change: Can Advanced MRI Techniques Predict Outcome?

Investigator: James Fink, MD;   Conditions: High-grade Glioma;    Status: Recruiting

PLX3397 + Radiation Therapy + Temozolomide for Newly Diagnosed Glioblastoma (20131088)
An Open Label Phase 1b/2 Study of Orally Administered PLX3397 in Combination with Radiation Therapy and Temozolomide in Patients with Newly Diagnosed Glioblastoma

Investigator: Marc Chamberlain, MD;   Conditions: Astrocytomas; Brain Cancer; Glioblastoma Multiforme; Glioma; Solid Tumors;    Status: Recruiting;   Study ID: NCT01790503

ANG1005 for Recurrent High-Grade Glioma (20140010)
ANG1005-CLN-03: A Phase II, Open-Label, Multi-Center Study of ANG1005 in Patients with Recurrent High-Grade Glioma

Investigator: Marc Chamberlain, MD;   Conditions: Glioma, Glioblastoma, Brain Tumor, Recurrent;    Status: Recruiting;   Study ID: NCT01967810

Radiation w/ Concomitant and Adjuvant Temozolomide or Radiation w/ Adjuvant PCV or Temozolomide Alone for Anaplastic Glioma (NCCTG 0577)
Phase III Intergroup Study of Temozolomide Alone Versus Radiotherapy With Concomitant and Adjuvant Temozolomide Versus Radiotherapy With Adjuvant PCV Chemotherapy in Patients With 1p/19q Co-deleted Anaplastic Glioma

Investigator: ;   Conditions: Brain and Central Nervous System Tumors;    Status: Recruiting;   Study ID: NCT00887146