Clinical Trials

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Brain/Spinal Cord Cancers

 

Depocyt-Methotrexate trial for Leptomeningeal Metastases (6954)
A Phase II Study of the Combination of High-dose Methotrexate and Intrathecal Liposomal Cytarabine in Patients with Parenchymal and Leptomeningeal Metastases from Breast Cancer

Investigator: Maciej Mrugala, MD, PhD;   Conditions: Stage IV Breast Cancer, Central Nervous System Involvement/Metastases, Leptomeningeal Metastases, Recurrent Breast Cancer, Tumors Metastatic to Brain;    Status: Open;   Study ID: NCT00992602

Bevacizumab Versus Bevacizumab Plus Vorinostat for Recurrent Glioblastoma (7994)
Phase I/II Adaptive Randomized Trial of Bevacizumab Versus Bevacizumab Plus Vorinostat in Adults With Recurrent Glioblastoma

Investigator: Marc Chamberlain, MD;   Conditions: Brain Cancer;    Status: Recruiting;   Study ID: NCT01266031

Celldex ReACT (UW12001)
A Phase II Study of Rindopepimut/GM-CSF in Patients with Relapsed EGFRvIII-Positive Glioblastoma

Investigator: Maciej Mrugala, MD, PhD;   Conditions: Glioblastoma Multiforme;    Status: Recruiting;   Study ID: NCT01498328

NW Avastin trial for Progressive or Recurrent Meningiomas (7329)
Phase II trial of bevacizumab (Avastin) in patients with recurrent or progressive meningiomas

Investigator: Marc Chamberlain, MD;   Conditions: Brain Cancer;    Status: Recruiting;   Study ID: NCT01125046

Radiation w/wo Temozolomide for Low-Grade Gliomas (RTOG-1072)
Phase III Study of Radiation Therapy With or Without Temozolomide For Symptomatic or Progressive Low-Grade Gliomas

Investigator: George Laramore, MD;   Conditions: Brain and Central Nervous System Tumors, Neurotoxicity Syndromes;    Status: Recruiting;   Study ID: NCT00978458

Bevacizumab w/wo Radiation Therapy for Recurrent Glioblastoma (RTOG-1205)
Randomized Phase II Trial Of Concurrent Bevacizumab and Re-Irradiation Versus Bevacizumab Alone as Treatment for Recurrent Glioblastoma

Investigator: George E. Laramore, MD;   Conditions: Adult Glioblastoma;    Status: Recruiting;   Study ID: NCT01730950

Radiation Therapy With or Without Temozolomide for Anaplastic Glioma (RTOG 0834)
Phase III Trial On Concurrent and Adjuvant Temozolomide Chemotherapy in Non-1P/19Q Deleted Anaplastic Glioma: The CATNON Intergroup Trial

Investigator: George Laramore, MD, PhD;   Conditions: Brain and Central Nervous System Tumors;    Status: Recruiting;   Study ID: NCT00626990

Imaging Study 7754
Cellular Proliferation Using [18F] fluorothymidine (FLT) Positron Emission Tomography (PET) in Brain Tumors

Investigator: Janet Eary, MD;   Conditions: Brain Tumor;    Status: Recruiting

Imaging Study 21213
Assessing Brain Tumors with [18F] Fluoromisonidazole (FMISO) PET

Investigator: Janet Eary, MD;   Conditions: Brain Tumor;    Status: Recruiting

Imaging Study 7185
Distinguishing Recurrent Glioma From Post-Radiation Change: Can Advanced MRI Techniques Predict Outcome?

Investigator: James Fink, MD;   Conditions: High-grade Glioma;    Status: Recruiting

PLX3397 + Radiation Therapy + Temozolomide for Newly Diagnosed Glioblastoma (20131088)
An Open Label Phase 1b/2 Study of Orally Administered PLX3397 in Combination with Radiation Therapy and Temozolomide in Patients with Newly Diagnosed Glioblastoma

Investigator: Marc Chamberlain, MD;   Conditions: Astrocytomas; Brain Cancer; Glioblastoma Multiforme; Glioma; Solid Tumors;    Status: Recruiting;   Study ID: NCT01790503