List All Brain/Spinal Cord Cancers Trials

Brain/Spinal Cord Cancers

Imaging Study 7185
Distinguishing Recurrent Glioma From Post-Radiation Change: Can Advanced MRI Techniques Predict Outcome?
Status Conditions Phase Study ID
Recruiting High-grade Glioma N/A 7185

To determine accuracy of advanced MR imaging parameters as well as the impact of the advanced MR tests on clinical outcomes of patients with treated glioma.

James Fink, MD
Seattle Cancer Care Alliance 800-804-8824  
Eligibility Criteria (must meet the following to participate in this study)
  • Newly or previously diagnosed malignant glioma, WHO grades II-IV based on pathology confirmation
  • Newly or previously treated with standard fractionated radiation therapy
  • Karnofsky performance status score >60
Exclusions (conditions that would prevent participation in this study)
  • Unable to provide a written informed consent; or under the care of a parent or legal guardian who is unable to provide written consent
  • Not suitable to undergo MRI or use the contrast agent Gadolinium because of:
    1. Claustrophobia
    2. Presence of metallic objects or implanted medical devices in body (i.e., cardiac pacemaker, aneurysm clips, surgical clips, prostheses, artificial hearts, valves with steel parts, metal fragments, shrapnel, tattoos near the eye, or steel implants)
    3. History of severe allergic reaction to intravenous contrast (iodine or gadolinium)
    4. Renal failure
    5. Reduced renal function, as determined by GFR < 30 mL/min/1.73 m2 based on a serum creatinine level obtained within 28 days prior to registration.
  • Presence of serious systemic illness, including: uncontrolled intercurrent infection, uncontrolled malignancy, significant renal disease, or psychiatric/social situations which might impact the survival endpoint of the study or limit compliance with study requirements.
Last Updated
September 18, 2013
Access protocol and consent forms at Fred Hutchinson Cancer Research Center
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  • Whether you are eligible for a research study depends on many things. There are specific requirements to be in research studies. These requirements are different for each study.